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Comment · Wed, January 13, 2021 · ND Owner

How long til peak plasma concentration of LM 8:1?

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18127153 · 5 points

Dealing with some Ed likely because of my brilliant choice to start with 2 grams a day right off the bat. Overly ambitious, I know. Anyone able to answer the title question for me? If this has been already posted I will delete later. Thanks in advance.

What they were answering

18127153 · 1 points

I think my question was poorly worded; you may have understood but I’ll clarify to be sure. I was wondering how many days/weeks etc of consistently dosing the same frequency and quantity would it take for my blood levels to plateau/reach max stability.

u/MisterYouAreSoDumb · ND Owner

Ahh, that's called steady state concentration/plasma levels. Peak plasma levels are usually in reference to the peak after a single dose. Steady state plasma levels are referring to when you reach a plateau after regular dosing. Usually these terms are only used for single compound things, though. That's because botanical extracts with tons of things in them will all have varying pharmacokinetics. It also depends on dosage. From a more colloquial perspective, lion's mane will generally build up effects over a 1-2 week period. However, that's a very rough estimate. We need a lot more human studies on it to say with certainty on some of this stuff.

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