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Comment · Wed, January 13, 2021 · ND Owner

4’-DMA-7,8-DHF Dose inquiry

Original post in this thread

JMac1536 · 27 points

So I tried 7,8-DHF for the first time a few months ago and was really impressed the results. I’ve had it in my rotation ever since. I find it helps me with energy, motivation, and focus, without that tweaked out feeling that some stimulating nootropics give me. I was perusing ND to reorder some of my normal supplements, and always like checking out the latest ones, when I stumbled across 4’-DMA-7,8-DHF. After doing some quick research I found it’s a more potent, water and lipid soluble, longer lasting TrkB agonist which is extremely appealing to me. Based on that information I can see why the suggested capsule dosage is 8mg as opposed to 25mg 7,8-DHF. My first question is what is a suggested dose range for 4’-DMA-7,8-DHF? My second is, will there eventually be a powder option alongside the capsule option like 7,8-DHF? Thanks in advance for the help guys!

What they were answering

JMac1536 · 5 points

I completely understand. I just wanted to get your opinion in particular since you have more knowledge about the nootropics from ND than anyone else. I’ll stick to the one capsule dose for sure then. Appreciate you answering about the powdered form as well. I’ll be sure to leave a review of my experiences with the 4’-DMA to give you guys some feedback on it after I’ve spent some time with it. By the way, I love Nootropics Depot, thank you for all you do! You guys have been my go to for all supplements for years now!

u/MisterYouAreSoDumb · ND Owner

Yes, please give me your feedback when you have some! That's the only way we can make better decisions and improve things.

For the dose of 4'DMA-7,8-DHF specifically, the dose/response curve is a lot more parabolic than regular 7,8-DHF. It's easier to overdo it with the 4'DMA version, which is why we are being more conservative. I am certainly interested to see how people respond in the real world, though.

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