Comment · Sun, November 22, 2020 · ND Owner
Questions about Quercetin bioavailability
Original post in this thread
BoozeAndHotpants · 10 points
I have read many conflicting studies on the relative bioavailability of Quercetin. I know there are manufacturers that use lecithin to create “phytosome” versions to increase absorption and utilization, but I also know that sometimes just taking a greater amount of a lesser bioavailable form is often the most economical option. Do you guys at ND (or anyone else) have any guidance or knowledge on this?
Here is an example for illustration purposes only; not speaking about the quality of the study at all, just to show the type of study that makes it confusing to pick a quality quercetin supplement:
https://www.nutraingredients-usa.com/Article/2018/10/30/Overcoming-the-low-bioavailability-hurdle-of-quercetin-Indena-study-supports-phytosome-use-to-boost-absorption
“Despite the potential benefits, bioavailability of quercetin is low with estimations that only 20% of the administered dose reaches the blood.
This is where Indena’s use of a delivery system based on food-grade lecithin offers a solution: According to data published in European Journal of Drug Metabolism and Pharmacokinetics the Quercetin Phytosome (Quercefit) proved to be up to 20-fold more bioavailable.”
What they were answering
solothesensei · 3 points
Mind sharing more about the side effects you got from EMIQ? I had the impression it was the most superior form of quercetin in the category (including dihydroquercetin and isoquercetin).
u/MisterYouAreSoDumb · ND Owner
Anxiety mostly. It might be the most bioavailable form, but that can be counterproductive in many cases. Perhaps it was just getting too much to my brain, and I was getting over-stimulated. There was not a dose low enough that I could avoid the side effects, so I had to drop it altogether. I can manage a 500mg dose of regular quercetin much better.