Comment · Mon, September 14, 2020 · ND Owner

Amount of piperine to inhibit CYP3A4?

What they were answering

xyz679 · 1 points

Quick question, I have both NA-R-ALA and R-ALA cyclodextrin, however from looking at that bioavailability study of R-ALA cyclodextrin(6000mg) vs just R-ALA(600mg) it looked like R-ALA-Cyclodextrin levels still drop to almost nothing at 1 hour even though they reach a much higher peak. Would dosing R-ALA-Cyclodextrin require a re-dose every hour instead of every 2 hours of roll like with NA-R-ALA?

u/MisterYouAreSoDumb · ND Owner

I honestly would limit redosing. Just do before and after. The during stuff just complicates things. Before and after will be just fine.

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