Comment · Fri, September 11, 2020 · ND Owner
Amount of piperine to inhibit CYP3A4?
What they were answering
Direct reply to the original post in this thread.
u/MisterYouAreSoDumb · ND Owner
I would personally avoid piperine in that instance. I actually suggest avoiding inhibiting CYP enzymes at all these days. Focus just on addressing the hydroxyl radicals with antioxidants instead.
Long-term tolerance is a tough one. We still don't fully understand all the mechanisms at play.