Comment · Tue, August 11, 2020 · Natrium Health & Nootropics Depot
Two clinical trials support GABA’s cognitive health benefits
Original post in this thread
ProperBeat · 59 points
Supplementation with GABA (gamma-aminobutyric acid) may boost a range of cognitive measures, including memory and spatial cognitive function, according to two new studies from Japan.
The results showed that 12 weeks of GABA supplementation at 100 mg per day led to significantly better tests scores for visuospatial/construction faculty and memory, and when the dose was doubled to 200 mg, additional improvements were recorded.
Note: both studies were funded by Pharma Foods International, which produces its GABA from the fermentation of Lactobacillus hilgardii using a proprietary process to over 80% purity, according to the company. The ingredient PharmaGABA, which is self-affirmed GRAS in the US, reportedly commands over 80% of the Japanese market.
What they were answering
gintrux · 5 points
Couldn’t it have indirect effects? I was looking for hdac inhibitors and found gaba is one https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201900001
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
For sure. GABA definitely has direct and indirect effects. My caution is more with the studies themselves than the idea that exogenous GABA supplementation could positively affect cognition.