Comment · Fri, July 24, 2020 · ND Owner

Polygala Sublingual Tablets

Original post in this thread

varvela · 11 points

First of all, I LOVE your Polygala extract. It’s precisely the Nootropic I’ve been looking for to give me the mental energy and focus to do my work for long periods of time. So hats off to you guys for this one.

What I’m wondering is if I could expect sublingual tablets/solution for the foreseeable future? It’s only that route of administration that gives me the right effect and I can’t exactly be weighing powders on my desk at work.

Secondly, side question, what in theory would Polygala do to the brain with chronic use (what kinds of up/down-regulations would occur for example)?

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · ND Owner

We are working on some sublingual tablet formulations. Polygala is one we are considering. Have you red our polygala blog yet?

https://nootropicsdepot.com/articles/top-benefits-of-polygala-tenuifolia-yuan-zhi/

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsDepotApr 21, 2021Nootropics DepotND Owner

Supply chain breakdown risks for Nootropics Depot?

Yeah, definitely true. Shit's fucked right now. It's not just our industry, either. It's ALL industries. I am replacing all the ACs at my house, and their is an air conditioner shortage. I am also replacing the roof righ

79Polygala

Commentr/NootropicsDepotNov 22, 2020Nootropics DepotND Owner

What mood boosters ACTUALLY work out there?

It's going to depend on the person. What works best for one person might do nothing for you, or have side effects. We like to talk in generalities, but people's brain chemistries vary a lot more than most realize. So fin

35Lion’s maneTongkat aliAshwagandhaPolygala

Commentr/NootropicsDepotJun 1, 2023Enforcement & pleaND Owner

⚠️ NEW PRODUCTS ALERT | Tiger Milk Mushroom Capsules, Coenzyme Q10 200mg Capsules, & Microzinc 40mg Capsules⚠️

Replying to Mcgrufer · u/MisterYouAreSoDumb and u/Pretty-Chill, what have been your experiences so far with Tiger Milk Mushroom? Given its rarity, there is little knowledge on this one. Additionally, cou…

The most immediate effect I notice is an improvement in breathing and a reduction in inflammation. It's pretty noticeable. There is some mild stimulation, and a cognitive/mood effect that is hard to put your finger on. I

29Lion’s manePolygala

Commentr/NootropicsDepotAug 11, 2020Nootropics DepotND Owner

How is polygala so amazing?

Replying to Majalisk · MYASD has mentioned there does seem to be some people who are essentially’super-responders’ to it, which is great for them

Yep, we have some customers that say polygala works better for them than anything else they have ever taken. Some of them have told me it has literally changed their lives. Then we have some people that are like "Eh, it'

23Polygala

Commentr/NootropicsDepotAug 20, 2020Nootropics DepotND Owner

Extended Release Polygala?

Yeah, we have thought about it. We just need to determine the best way to formulate that. We are also considering doing sublingual polygala tablets.

19Polygala

Commentr/NootropicsDepotDec 30, 2020Nootropics DepotND Owner

Is polygala a strong enough MAOI that it shouldn’t be combined with aniracetam?

No, it's not something you need to worry about. The main compound in polygala that has MAOI effects is called DISS (3,6'-disinapoyl sucrose). It has less than 0.5% bioavailability. This means it is likely not clinically

18AniracetamPolygalaRacetams