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Comment · Fri, May 1, 2020 · Natrium Health & Nootropics Depot

FDA's Letter to Tailor Made Compounding Pharmacy

What they were answering

dlew1453 · 1 points

I have seen automated peptide synthesizers going for about 15k to 20k online. Is it complicated to operate one? My dream scenarios would involve just buying a bunch of amino acids, pouring them into the machine, typing in a peptide sequence, pressing a button, and then taking a nap while my peptide batch is cooked up. I'm guessing it's probably not that simple at all...

u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot

As with any lab equipment, buying it is only the start of the story. You need all the peripherals to run it. You need precursors and supplies. You need maintenance contracts and IQ/OQ run to ensure it is working as it is supposed to, then you need qualified people to operate it. Most of the time the machine is the cheapest part. Synthetic chemists are rare and expensive in the US. One that understand liquid phase and solid phase peptide synthesis? Even more so. Then you need time. You need time to work through you processes to get proper yields. Then you need to test that your product was correctly made. So you need HPLC/UPLC, mass spec, and maybe NMR. It is not simple, cheap, or easy.

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