Comment · Tue, February 4, 2020

Can you provide explanation of the change in 8:1 Lion's Mane extract?

Original post in this thread

YoYoYL · 6 points

You mentioned in a post that you have a new source for Lion's Mane.

Can you please specify what changed and why? How is the extract method affected?

Looking to get best NGF results.

Also, do you where can I find purity tests for Piracetam and phenylpiracetam?

Are there any other supplements proven to enhance CSF in the brain?

What they were answering

Chargers95 · 1 points

Assuming they didnt mean CSF (cerebralspinal fluid), I do have the question - do you know anything that certainly does improve CSF function or decrease permeability of the BBB? Especially that isnt magnesium as this gives me major digestive issues?

It's an extremely overlooked problem post concussion, and there isnt much you can find on it.

u/MisterYouAreSoDumb

That's kind of a complex and not-fully-understood effect. Ghrelin seems to help.

https://www.liebertpub.com/doi/abs/10.1089/neu.2011.2053

Activation of the α7 nicotinic acetylcholine receptor seems to as well.

https://www.jneurosci.org/content/36/9/2809.short

Citicoline/CDP-choline seems to activate that receptor.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660732/

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