Comment · Sun, December 29, 2019
NMN - Worth the money?
Original post in this thread
hwtu · 15 points
Hello, is taking NMN worth the money?
What they were answering
gzmst · 1 points
What about ProHealth? : https://store.prohealth.com/
They have been around for decades and make supplements catered to people with chronic fatigue syndrome and fibromyalgia. Their founder has cfs himself.A couple of years ago they had a Niagen product called Nad+ Ignite but just as many other brands they discontinued it.
They now have a second webstore called ProHealth Longevity and they sell NMN products:https://www.prohealthlongevity.com/collections/nmn
On their website they have certificates of analysis, including testing for heavy metals:https://cdn.shopify.com/s/files/1/0206/3076/5668/products/PH518\_COA\[email protected]?v=1574810825
u/MisterYouAreSoDumb
That's the same lab that Alive By Nature uses. If you look deeper at their COAs, you can see they are using the same test method number, MQLTM-1126, for different methodologies... So one of their tests says MQLTM-1126 for HPLC, and completely different test result says MQLTM-1126 for IC, or ion chromatography.
Different methodologies should have different methods, and certainly different method numbers. It could be a clerical mistake, but I would need some explanation before I would write it off.
They are not ISO certified for NMN testing, either. Their certification is limited to only a few of their tests. My lab director actually contacted them to ask about all this, and they were unwilling to give us any details on their testing or validation for NMN. It raised a lot of red flags to us. Also, they claim their detection limit on the ICP-MS for heavy metals is 3 parts per BILLION, or 0.003ppm, and that 3 of the metals were not detected at all. That's unlikely. You would see some on there at a 3ppb detection limit. It makes me question the validation and optimization of those methods. I would need to see some method and validation data before I would be comfortable trusting those results. It could be fine, but I have seen too many labs using questionable data and methods to just accept them at face value.
In this video they say that they get their NMN from the same company that supplies research universities: https://www.youtube.com/watch?v=CUbNGACHMQk
That video suspiciously uses the same language as Alive By Nature, with saying it is "triple tested." That's a weird thing to say, as that doesn't mean anything, and neither of them actually show lab data from 3 labs. I only see data from two labs on Alive By Nature, and one of them looks much sketchier than Micro Quality. ProHealth only has one lab's results. They might be saying that because Alive By Nature is, but it all seems strange to me. Also, anyone can claim anything they want. I see people claiming they use the same suppliers as research universities all the time. Without verification, those are just words. Even if it is true, that doesn't really mean anything about the quality of the batches they get. Their stability data is interesting, too. I would love to see the lab data backing up the numbers in that table.
That being said, at least ProHealth is ordering heavy metals testing, which Alive By Nature doesn't seem to be. So at least they are trying to test that, even if I am not certain of the reliability of the results from that lab. I would need to see results from a lab I trust, or a lot more method and validation data from Micro Quality, before I would trust it.