Pomegranate compound with anti-aging effects passes human trial

Comment · Mon, June 17, 2019 · 21 pts

Urolithin A is a metabolite of the punicalagins in Pomella. There are even studies on Pomella and this compound. We mention Urolithin A on our product page as well. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359844/

Comment · Mon, June 17, 2019 · 17 pts

The punicalagins that lead to increased levels of Urolithin A are highest in the husk of the pomegranate. So you would need to eat that nasty husk to get them. An extract is much more feasible.

Comment · Tue, June 18, 2019 · 6 pts

I don't offhand. I am speaking with my lab manager now about using the AOAC punicalagin testing method to estimate how much urolithin A you might get. It is going to depend on your gut microflora, though. So it is not an

Comment · Tue, June 18, 2019 · 6 pts

He is talking about the bioavailability of exogenously supplemented ellagic acid, not its ability to be converted in-vitro in a controlled study. Its bioavailability has been questioned in the past, but those studies may

Comment · Tue, June 18, 2019 · 3 pts

The husk is the whole outside of it. You could blend the whole pomegranate and consume it all. It will just be bitter.

Comment · Fri, June 21, 2019 · 2 pts

I never suggested it did. The person you were responding to may have been trying to make that point. However, I was just linking to a study that was discussing the limitations of supplementing free EA, because I had also

Comment · Thu, July 4, 2019 · 1 pts

Possible, if we can make the numbers work.

Comment · Thu, July 4, 2019 · 1 pts

Any brand new product like this would realistically be at least 2-3 months off at minimum. There's a lot of leg work we need to do these days to bring new things out.

Comment · Tue, July 16, 2019 · 1 pts

It's not a direct relationship, as it depends on your probiotics to convert it. So we can't really say X amount of Pomella will lead to Y amount of urolithin A. We are working on a direct supplement for urolithin A, thou

Comment · Wed, July 17, 2019 · 1 pts

Yes https://www.acs.org/content/acs/en/pressroom/presspacs/2015/acs-presspac-december-9-2015/pomegranate-may-help-against-alzheimers.html >Computational studies found that polyphenols could not cross the blood-brain ba