The synthesis for Imidazenil is underway.

Comment · Sat, March 16, 2019 · 7 pts

That's a pretty complex thing to answer without more info. It seems to act as more of a partial positive allosteric modulator than a full agonist. I would not really be comfortable guessing without at least first trying

Comment · Sat, March 16, 2019 · 3 pts

You're right, all benzos are positive allosteric modulators of GABA. It's barbiturates that act as a full agonist at high concentrations. The variations in benzos are due to subtype selectivity. This was the study I wa

Comment · Sat, March 16, 2019 · 4 pts

Have you looked into emoxypine? That increases the binding affinity for the GABA receptor. It's a Russian study, but it is translated: https://cyberleninka.ru/article/v/rol-oksidativnogo-stressa-i-antioksidantov-pri-de

Comment · Sat, March 16, 2019 · 1 pts

I would venture to guess you are going to be right. Always treat things like this with a lot of care. Don't believe any anecdotes about not causing tolerance. That's a recipe for disaster.

Comment · Sat, March 16, 2019 · 3 pts

Very disputable. The blogs hyping up etizolam as a completely safe and non-tolerance-forming compound are incredibly dangerous. I've found the exact opposite with etizolam, personally. It's far more likely to give me reb

Comment · Wed, March 27, 2019 · 1 pts

We don't have the bandwidth for any side projects at the moment. My lab is buried just with our own testing, and we are sending a lot off to 3rd party labs right now as it is. For Imidazenil, we would be starting from sq

Comment · Thu, March 28, 2019 · 1 pts

Probably not at the moment. I have so much going on, and my risk tolerance for personal trials has gone way down with the amount of responsibility I have now. I'd try it down the line, once we have some valid reference s