Comment · Sat, December 16, 2017 · Ceretropic & Nootropics Depot

Lions mane: extract or powder, what is suggested?

What they were answering

biohackislife · 2 points

I completely agree. Hopefully we are closer to proving that with some HPLC methods we recently found. The main problem with the cultured mycelium extract is that the only Erinacine A standard I can find is like $22,000 for 5mg, or something crazy like that. Since you have been finding some standards I seem to have missed lately, perhaps you know of a more reasonable Erinacine A standard? Quantifying the other NGF-promoting compounds in the fruiting bodies is a bit harder, as they have only recently been elucidated. It seems that even Amyloban is only standardized to hericenones. So even that extract, while still having human clinical research, can't factually prove it is increasing NGF. A lot more needs to be done in this area to set proper standardizations for lion's mane.

That would be excellent.

Yes. You can try.

http://www.musechem.com/product/R030854.html

Amyloban states they are standardized for hericenones (0.5%) and amyloban 6% (dilinoleoyl-phosphatidylethanolamine (DLPE) and hericenone derivatives) as well.*

You are quite correct there is no direct evidence of NGF effects in humans from Lion's mane. Compared to herbal extracts with well defined bioactives Lion's mane has quite a ways to go but that certainly does not stop us from trying it in the hopes of seeing NGF related benefits based in part on benefits seen in clinical research.

Ultimately at this point…

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Thanks for the MuseChem link! I will submit a request to see if they can get us a standard for a somewhat reasonable price.

This is the one we found before: https://www.trc-canada.com/product-detail/?E600090

$22,500 for 5mg. Only $27,150 for 10mg, though! So that's a steal. Haha

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