Mk-677

Comment · Sat, May 21, 2016 · 4 pts

Still impure. So far all 6 batches this year, from multiple suppliers, has been impure. It's a solvent residue with a carbonyl group, which is giving an extra peak at about 1,730-1,740 cm-1. HPLC shows the impurity is a

Comment · Mon, May 23, 2016 · 5 pts

Ohh, I am giving them more than feedback. Trust me. They just do not seem to give a shit, because MK-677 is in such high demand. They know if I reject it, someone else will buy it. I've even had people PMing me asking if

Comment · Mon, May 23, 2016 · 1 pts

Well we don't have the equipment or expertise to do our own synths yet. So for now I am at the mercy of other labs. I am still working on it, though. I will keep pushing them.

Comment · Mon, May 23, 2016 · 2 pts

I did not know you went to the hospital. This shit is dangerous, and it's shitty that other vendors just do not care.

Comment · Tue, May 24, 2016 · 3 pts

I would bet a lot of money they are not doing jack shit for testing. We just tested some of their CJC-1295 non-DAC, and it was not a clean read on the HPLC, even though our CJC was a 98.92% using the same methods. I am h

Comment · Tue, May 24, 2016 · 2 pts

I wish it were that simple. It's not only the equipment, but the space, expertise, synthesis methods, precursors, etc. Then there is no way we'll be able to do it for the same per mg price as an established lab. Perhaps

Comment · Tue, May 24, 2016 · 1 pts

Freelance chemists? Not sure if that is a thing.

Comment · Tue, May 24, 2016 · 1 pts

Benzyl chloroformate becomes phosgene gas when exposed to water. That was used as a chemical weapon in WWII. I would probably avoid doing that.

Comment · Wed, May 25, 2016 · 1 pts

Ohh, ok. So if you keep the temperature down, it will only release HCL fumes. Still dangerous, but not as bad as phosgene. I would think a rotary evaporation would be better to get rid of the residue, though. It's boilin

Comment · Wed, May 25, 2016 · 2 pts

Even research would be thrown off by a shitty synth with toxic impurities. There is no excuse.

Comment · Wed, May 25, 2016 · 1 pts

I have not run the numbers. The upfront cost to build a lab capable would be pretty high. Then I would still need to find a competent chemist, and secure precursors.

Comment · Wed, May 25, 2016 · 1 pts

Yeah, I have been considering that one.

Comment · Wed, May 25, 2016 · 1 pts

I would only be guessing, but I would imaging $500K to $1M.

Comment · Wed, May 25, 2016 · 3 pts

Haha, I guess. I'd need to find space for it too, because we have outgrown even our new facility. I've got 24 employees now, and we have used pretty much every inch of space we have. We are also starting to get automated

Comment · Fri, June 3, 2016 · 1 pts

If it was made in March 2015, then that was before all these quality issues started. They must just not go through it fast, or they are giving you an old COA. I'd call the lab to confirm the analysis at least. Superior