Comment · Wed, May 25, 2016 · Ceretropic & Nootropics Depot
Reishi cramps/diarrhea, any Reishi gurus here?
Original post in this thread
charrednoot · 4 points
About 2-3 weeks into taking Reishi, I started getting a sharp pain somewhere in my stomach area followed by diarrhea lasting throughout the day. I've only done Reishi for that long of a period once (that one time), after which I stopped.
Now I've heard that some adverse, "detoxification" effects could be common a few days in, but... not 3 weeks into it? That being said, I only took 1 capsule a day (as opposed to a suggested serving of 2-4 daily).
I'm fairly certain it was the Reishi because when I stopped taking it and resumed a few days later, the diarrhea stopped and then returned, and I had eaten no other suspect foods that could have triggered it to return.
Do you think this is part of the detoxification process, or is this more likely an individual case of me reacting adversely to it? I enjoy the effects. I get a high on the first or second day (extremely noticeable), otherwise I notice a mild calming/anxiolytic effect and noticeably decreased physiological responses to anxiety. If I just need to fight through some sort of detoxification stage, I'd like to continue using it.
What they were answering
Debonaire_Death · 1 points
M cells within the Peyer’s patches physically transport the insoluble whole glucan particles into the gut-associated lymphoid tissue.
Oooh is that how the immunomodulatory effect of the beta-glucans is instigated? I didn't really think about the huge amount of lymphoid tissue in the GI tract!
The concentrated extract should have less diuretic effect, due to having lower amounts of ACE inhibitors.
So the cardiovascular benefits will also be less with a more concentrated extract? I know the triterpenoids can help with coronary heart disease risk, but do they have any acute effects the way ACE inhibition does?
I actually don't know a lot about triterpenoids. Do you have any good sources for literature you could point me towards? I'll be happy to do the digging with a point in the right direction: you've already dedicated so much time to my questions!
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
So the cardiovascular benefits will also be less with a more concentrated extract? I know the triterpenoids can help with coronary heart disease risk, but do they have any acute effects the way ACE inhibition does?
They will be different, but not necessarily worse. I would think it would not be as acute of an effect. But I don't have data on that.
There are a lot of different triterpenoids. The triterpenoids in Reishi are called ganoderic acids.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271404/
Bitter triterpenoids from the fungus Ganoderma applanatum
So not all triterpenoids are the same, or lead to the same effects. It's best to concentrate your search on the ganoderic acids if you are wanting to learn more about Reishi's effects.