Comment · Mon, May 9, 2016 · Ceretropic & Nootropics Depot

Why is there such little information on N-Acetyl Semax Amidate or N-Acetyl Selank?

What they were answering

PartySunday · 7 points

Honestly I wouldn't be surprised if the pharmacokinetics also changed with the acetylation/amidation.

N-acetyl L-Tyrosine has different pharmacokinetics than L-Tyrosine. There are a lot of unknowns.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Of course the pharmacokinetics are different. That is the whole point! Did you mean to say pharmacodynamics? Pharmacokinetics is how the compound is absorbed, distributed, metabolized, and excreted. Acetylating and amidating of peptides is a very common modification to improve its pharmacokinetics.

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