Comment · Tue, April 26, 2016 · Ceretropic & Nootropics Depot
Is there any evidence that Soya Lecithin contains phytoestrogens?
Original post in this thread
GDMFusername · 2 points
I use Soy Lecithin as a choline source for the suggested benefit with Racetams. In the past I've read case studies of men who have developed gynecomastia and other issues as a result of consuming soy products. Is it possible that these soy-derived supplements contain phytoestrogens in significant amounts?
What they were answering
proudboner · 1 points
Raloxifene is actually one of the compounds in wide use that's closest to the holy grail of a neuroSERM (a SERM exclusively selective for brain tissue that has the neuroprotective effects of estrogen without the feminization). Its neuroprotective effects are much closer to that of estrogen than tamoxifen's are, anyways (while still antagonizing the HPTA).
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149792/#__sec5title
http://www.ncbi.nlm.nih.gov/pubmed/24726471
I wonder if there could be a modification to Raloxifene that allows it to penetrate the BBB better while not modifying its neuroprotection. That would be amazing for people on high dose Test or (even worse) Tren that are concerned about the negative effects androgens have on spacial cognition in the long run (which is suspected to be due to the fact that excessive androgen signalling not balanced out with the neuroprotection of estrogen causes neural apoptosis).
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
Yeah, Raloxifene is pretty useful in that aspect. I am sure someone is working on making it pass the BBB better.