Mk 677 Stock

Comment · Thu, April 14, 2016 · 8 pts

We had two batches come in from the main two labs making MK-677. They were only about 94% pure. We sent off to another lab for another opinion, and they ran it with UPLC, which is even more sensitive. They came to the sa

Comment · Fri, April 15, 2016 · 3 pts

It will still work fine. It will just be making you consume impurities. I cannot say how adversely that will affect you, as we don't know the exact impurities. I could mass spec it, and get a good idea. However, it's not

Comment · Fri, April 15, 2016 · 2 pts

Yeah, if either of these new synths turns out to be pure, I am going to buy it all.

Comment · Fri, April 15, 2016 · 3 pts

Yeah, there certainly could be. Benzyl chloroformate can be used as an intermediate in the synthesis of MK-677. Benzyl chloroformate becomes phosgene when exposed to water, which is a toxic gas. You certainly do not want

Comment · Thu, April 28, 2016 · 2 pts

I've never really heard of them. I'll make a note about their MK-677.

Comment · Thu, April 28, 2016 · 3 pts

That's no fun! Some of the compounds used in the synthesis of MK-677 are pretty nasty. If they put out a shitty synth, I could see the impurities causing some issues like that. That's why we are so strict with what we wi

Comment · Fri, April 29, 2016 · 1 pts

Yes, it's the mesylate salt. All MK-677 out there is the mescylate salt. We run FTIR for identity and HPLC for purity, and test it against a Sigma Aldrich reference standard. We even sent this last batch off to a 3rd par

Comment · Fri, May 6, 2016 · 5 pts

The new batch was just delivered! So after I answer my messages and emails, I'll head into the lab to analyze it. Cross your fingers! It certainly looks like a much better synth than the last few. So that is good.

Comment · Tue, May 10, 2016 · 4 pts

Yep, both of the new batches came in impure. They have a ton of benzyl chloroformate in them, which is a nasty toxin. Literally all batches of MK-677 we have received this year have been tainted with benzyl chloroformate

Comment · Mon, May 16, 2016 · 2 pts

Well every supplier screws up. This supplier that sent the 94% pure batch was the same supplier that sent the last over 99% one. That's why it's been so frustrating. If I could just stick to one supplier, and always be g

Comment · Mon, May 16, 2016 · 1 pts

Yeah, it is very stable in solution. It should be potent for at least 2 years, as long as it is kept out of the sun and high heat.

Comment · Tue, May 17, 2016 · 1 pts

It's definitely not ideal right now with the MK-677 market.