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Comment · Fri, February 19, 2016 · Ceretropic & Nootropics Depot

Methylphenylpiracetam

Original post in this thread

Doomnerve · 14 points

Was just browsing wikipedia and discovered this while browsing the racetam section.

https://en.m.wikipedia.org/wiki/Methylphenylpiracetam

Anyone heard of this before? Curious as to why no one carries it or talks about it. And no Google results whatsoever.

Seems like it would be an even more potent form of phenylpiracetam

What they were answering

cozyrain · 2 points

Cool. There is good reason to want to synth a sigma-1 PAM (like methylphenylpiracetam). It is that sigma-1 allosteric modulation is known to have antidepressant activity: https://www.ncbi.nlm.nih.gov/pubmed/26854125

That's a bonus on top of the expected nootropic activity of MPP.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Ohh trust me, I really want to try it too. Sigma-1 modulation is an area I really want to investigate more. If I had my own synthesis lab, I would have already done it.

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