Comment · Mon, November 16, 2015 · Ceretropic & Nootropics Depot
Ephedrine and tianeptine experience. (Be careful combining these two!)
Original post in this thread
sayitaintsoap · 21 points
I've been taking Tianeptine for almost 6 months consistently now, from sodium to sulphate. My dosage ranges from 12.5 mg t.i.d. to 20 mg t.i.d to 40 mg q1d depending on which version I'm taking. Just a few days ago I decided to start taking this thing called the ECA stack (ephedrine/caffeine/aspirin) to hopefully help burn a bit of fat and lose weight. The dosages have been 25 mg of ephedrine, 200 mg of caffeine, and 150 mg of aspirin. A few hours after taking all of this plus tianeptine, I experienced an insane analgesic effect. My sensation of touch was so numb I could barely feel my face with my hand. I remember thinking to my self that this must be what a heavy dose of morphine or other opioid must feel like. At first I thought it was the aspirin potentiating the opioid affinity property of tianeptine but couldn't find any literature supporting this theory. Then I researched ephedrine+opioids and found it.
http://www.ncbi.nlm.nih.gov/pubmed/8067229
Morphine-ephedrine interaction on analgesia was studied in mice (n = 240) and in post-operative patients (n = 32). It was found that combining morphine and ephedrine enhances analgesia which is not significantly different from the…
What they were answering
Debonaire_Death · 1 points
I'm very interested in trying to formulate a topical vasodilator. Something that would have a more localized effect. I'm thinking perhaps beta alanine and DMSO? That requires a higher dosage to be systemically active, which I think would mitigate central effects from it's use as a topical. I wish I had some sort of delivery solvent besides DMSO, but hey, it's been working nicely for me with minimal complications.
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
That would probably work. DMSO would be the best for topical applications, and beta alanine should give a good local effect.