Comment · Thu, August 13, 2015 · Ceretropic
Ephedrine and tianeptine experience. (Be careful combining these two!)
Original post in this thread
sayitaintsoap · 21 points
I've been taking Tianeptine for almost 6 months consistently now, from sodium to sulphate. My dosage ranges from 12.5 mg t.i.d. to 20 mg t.i.d to 40 mg q1d depending on which version I'm taking. Just a few days ago I decided to start taking this thing called the ECA stack (ephedrine/caffeine/aspirin) to hopefully help burn a bit of fat and lose weight. The dosages have been 25 mg of ephedrine, 200 mg of caffeine, and 150 mg of aspirin. A few hours after taking all of this plus tianeptine, I experienced an insane analgesic effect. My sensation of touch was so numb I could barely feel my face with my hand. I remember thinking to my self that this must be what a heavy dose of morphine or other opioid must feel like. At first I thought it was the aspirin potentiating the opioid affinity property of tianeptine but couldn't find any literature supporting this theory. Then I researched ephedrine+opioids and found it.
http://www.ncbi.nlm.nih.gov/pubmed/8067229
Morphine-ephedrine interaction on analgesia was studied in mice (n = 240) and in post-operative patients (n = 32). It was found that combining morphine and ephedrine enhances analgesia which is not significantly different from the…
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Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · Ceretropic
Interesting. I have combined Tianeptine with my ECA stack before, and did not have an issue. I never use Aspirin in the stack, though. I replace it with L-Arginine, L-Citruline, CoQ10, Taurine, EGCG, and Ornithine.