Comment · Fri, June 12, 2015 · Ceretropic
Contacted researcher to experiment with NSI-189 on human blood cell cultures, need help finding prestigious supplier in Israel
Original post in this thread
EK777XX · 11 points
Hello,
Contacted the researcher from Tel Aviv University (TAU) behind this study in which he is analyzing what genes activate/deactivate with SSRI administration.
(see: Serotonin deficiency may not cause depression after all http://www.salon.com/2013/12/13/new_developments_may_help_those_with_depression_partner/)
I asked him if he may replicate the same study with NSI-189, which is funded by DARPA for the treatment of MDD (Major Depressive Disorder), to see if bear any correlation with SSRIs. I also told him I wondered if this could shed light more on how antidepressants work and better treatments for depression (maybe someday a cure). He said yes.
I am needing help of knowledgable users (researchers, chemists, etc) that can recommend a reputable source of NSI-189 with a representative in Israel, because the researcher needs such source quality in order to be able to publish such findings in a formal study. Here's the quote:
// I prefer to wait till a reliable company, such as Sigma Aldrich, Calbiochem etc will have it. With a supplier such as the current ones it will not be possible to publish the findings in a good scientific journal.As you are following this compound, I wil…
What they were answering
EK777XX · 3 points
*Update Jun-11-2015: Researcher replied that from his experience, this is unlikely--
// From my experience with requesting compounds from companies, this rarely work. Even if it does, it take months to get the MTA signed by the university legal office. So I will rather wait few months of even one year till NSI-189 becomes available from a reliable resource and with an agent in Israel (all large suppliers of research chemicals have an agent in Israel).//
u/MisterYouAreSoDumb · Ceretropic
If it an internal legal issue from the university, then you might have to wait. Neuralstem has been pretty protective of NSI-189. They might not even want anyone researching its effects on gene expression yet.