Comment · Thu, June 11, 2015 · Ceretropic
Contacted researcher to experiment with NSI-189 on human blood cell cultures, need help finding prestigious supplier in Israel
Original post in this thread
EK777XX · 11 points
Hello,
Contacted the researcher from Tel Aviv University (TAU) behind this study in which he is analyzing what genes activate/deactivate with SSRI administration.
(see: Serotonin deficiency may not cause depression after all http://www.salon.com/2013/12/13/new_developments_may_help_those_with_depression_partner/)
I asked him if he may replicate the same study with NSI-189, which is funded by DARPA for the treatment of MDD (Major Depressive Disorder), to see if bear any correlation with SSRIs. I also told him I wondered if this could shed light more on how antidepressants work and better treatments for depression (maybe someday a cure). He said yes.
I am needing help of knowledgable users (researchers, chemists, etc) that can recommend a reputable source of NSI-189 with a representative in Israel, because the researcher needs such source quality in order to be able to publish such findings in a formal study. Here's the quote:
// I prefer to wait till a reliable company, such as Sigma Aldrich, Calbiochem etc will have it. With a supplier such as the current ones it will not be possible to publish the findings in a good scientific journal.As you are following this compound, I wil…
What they were answering
not_a_amoeba · 1 points
I believe this is general convention of the scientific community. Regardless of whether it seems reasonable or logical, it is undeniably the current situation in research and something you have to abide by if you want your publications taken seriously.
u/MisterYouAreSoDumb · Ceretropic
I've had Sigma Aldrich reference samples turn out to be less pure than our lab's sample before. There is also an FTIR spectral database entry for 7,8-Dihydroxyflavone from Sigma Aldrich that I am seriously questioning the validity of. Their FTIR standard is not jiving with our HPLC and NMR testing, nor does it match 3 other samples we acquired online. Either all our testing is wrong, and all the other suppliers samples are wrong too, or Sigma has a bad standard for 7,8-DHF. This is seriously leading me to question whether or not we can implicitly trust any "name-brand" supplier. Perhaps the general consensus needs to change.