Comment · Fri, June 12, 2015 · Ceretropic
MK 677 cures hangovers
Original post in this thread
lifthard_swouler · 34 points
A couple of days ago, I went out and partied the night before and important meeting. I drank a little (lot) too much and woke up with a pretty bad hangover the next day.
In a hail mary attempt to not feel like shit and be able to make the meeting, I randomly decided to take 25mg of MK 677 that I had leftover from an experiment. It was about a month since I had last taken it.
It worked! My nausea and sickness was quickly replaced with an extreme hunger. Rather than nibbling on a piece of toast with some Gatorade, as I normally would when I'm hungover, I smashed 5 eggs, 2 pieces of toast, and 3 glasses of orange juice.
I still had a minor headache for the rest of the day, but nothing even remotely close to how shitty I felt before taking MK677.
What they were answering
rmcfar11 · 2 points
As a side note, long term opiate use decreases testosterone. I suppose that is not surprising if it increases IGF-1. If opiates are used in high doses and/or over long periods of time, it's not something that reverts back afterwards. I'm sure it does eventually, but it's still a relatively new correlation that's been observed. (To my knowledge at least)
u/MisterYouAreSoDumb · Ceretropic
Yeah, that is a common effect from opioids as well. Did you see the link I posted in the other comment? That goes through a ton of endocrine effects from opioids. They increase growth hormone and prolactin, while decreasing testosterone, estradiol, and oxytocin.