Comment · Fri, April 24, 2015 · Ceretropic
Tianeptine sulfate is so great.
Original post in this thread
cameronhook · 23 points
I've never tried tianeptine before, but I bought the sulfate version to try out. I'm meant to be on 75mg of zoloft but I only take 50mg because 75 causes migraines. I am continously depressed, the zoloft helped my panic disorder and ocd but if anything made my depression worse. Everyday is just mood swings and wishing I could die.
But, today for the first time I took 40mg tianeptine sulfate with my zoloft. It's been about 6 hours since and I feel great, finally normal, happy and able to enjoy my girlfriends company instead of wanting her to leave me alone. I dunno if this will disappear in time but it is just so great to be happy for once.
What they were answering
galmse · 1 points
Oh yes, sorry, I didn't mean to imply that the difference wasn't significant, and should probably have highlighted time along with bioavailability / dissolution.
A fourfold increase in plasma concentration at peak would of course influence all drug effects; I just meant that the mechanism by which Tianeptine might worsen EPS wouldn't be affected by the form in which it is delivered.
u/MisterYouAreSoDumb · Ceretropic
Yeah, the mechanism would be the same. However, it might not manifest with a smoother plasma curve. I wish I could read the study.