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Comment · Thu, January 22, 2015 · Ceretropic

Semax and libido

Original post in this thread

[deleted] · 3 points

So I've been taking Semax (nasal spray version from Ceretropic) daily for approximately 2 weeks now in dosages of 600-1000mcg and I've noticed a decrease in libido.

Not sure if it's caused by Semax but I'll stop using it for now to see if anything changes.

Was wondering if any of you had similar experiences with Semax?

What they were answering

EnLilaSko · 1 points

The difference is that Melanotan II is an agonis while semax in an antagonist, so it would reduce libiod (or atleast erections).

u/MisterYouAreSoDumb · Ceretropic

Yeah, that is true. MTII agonizes, while ACTH 4-10 antagonizes. For some reason I was under the impression that Semax activated the melanocortin system. Even though it only has ACTH 4-7, I would assume it's actions on the MC4 receptors would be similar to ACTH 4-10. Although I am having a hard time finding that info in the studies I have.

Do you have the study showing Semax, or ACTH 4-7, antagonizes the MC4 receptor?

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