Comment · Tue, September 30, 2014 · Ceretropic
What they were answering
AudioCasanova · 1 points
Ahh yes, that makes sense. Which route did you prefer for P21?
u/MisterYouAreSoDumb · Ceretropic
So far I prefer nasal.
Comment · Tue, September 30, 2014 · 4 pts
That's an interesting proposition. I have no doubt it could be done. But how would we control the stability of the peptide on patches during shipping? How would we protect it from ions in the air, light, and heat, while
Comment · Tue, September 30, 2014 · 6 pts
I think nasal is the most promising, easiest to produce, and most convenient for the consumers to use. It's only roughly 70% efficient, but that is enough to justify the route. Not to mention, nasal gets peptides to your
Comment · Tue, September 30, 2014 · 4 pts
Well heat needs ions to catalyze the breakdown. If we could eliminate the ions in the solution, by using deionized water, and keep air away from the solution on the patch, then it should be stable long enough to get thro
Comment · Tue, September 30, 2014 · 1 pts
I think it is more about the time to reach peak plasma levels in the brain. Nasal seems to get to the brain faster, even if there is a slight loss due to the inefficiency of the nasal mucosa.
Comment · Tue, September 30, 2014 · 2 pts
This isn't the It Works! wraps. Haha. They would be small patches, and would not cause sweating.
Comment · Tue, September 30, 2014 · 2 pts
I can be, yes. Also, there is evidence that instranasal bypasses the blood brain barrier faster, so that is playing a role as well.
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