Comment · Fri, August 29, 2014 · Ceretropic
Hydrafinil Report
Original post in this thread
[deleted] · 22 points
I received my shipment of Hydrafinil a few days ago and have dosed it 4 times at this point and feel as if I can give some good feedback as to it's effectiveness (on my own chemistry at least). Currently I am not stacking any other substances except for Magnesium Citrate and a Multivitamin and Nicotine Vaporized.
Day 1 - 53mg Hydrafinil (2x)
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>T:0 - Ingested the powder (odd consistency reminds me of Alpha-GPC, not sure if it's hydrophilic or something along those lines?)
>T:+30m - Started to feel the effects of the initial dose beyond what I imagine to be placebo. I'm generally slightly fatigued due to sleep deprivation for my working schedule this fatigue was removed almost completely.
>T:+1h - Effects are in full swing. This dosage is reminiscent of the higher doses of Adrafinil that I have tried however it feels cleaner subjectively. The wakefulness promotion given by Hydrafinil can only be described as clean stimulation (not in the same vein as standard stimulants).
>T+1.2h - Slight euphoria has been noted at this point. Not anything to write home about but I was getting a little bit more pleasure out of day to day activities.…
What they were answering
baronjpetor · 1 points
I've noticed a strong cross-tolerance between modafinil and amps (2-FMA in my case).
I know that Hydrafinil is not really chemically related to Moda but should we expect the same thing ?
By the way, 5-HT6 antagonism looks interesting... Any potential interaction with other serotonergic substances ?
u/MisterYouAreSoDumb · Ceretropic
No, it will not have the same cross-tolerance, since there are lower DAT affinities. It still might have some, but it should not be as much.
It should not interact with other serotonergic substances, since it does not really control serotonin release. Blockage of the 5-HT6 receptor increases dopamine and norepinephrine, but not 5-HT, to my knowledge.