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Comment · Mon, July 28, 2014 · Ceretropic

NSI-189 producing company´s CEO writes about it´s nootropic effects.

Original post in this thread

cobue · 33 points

Nootropics

Posted: October 25th, 2013

(/noʊ.əˈtrɒpɨks/ noh-ə-trop-iks), also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that purportedly improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.

In a recent article about Neuralstem, Dr. Johe was asked about the potential cognitive implications of our first in class neurogenic compound NSI-189. Although the drug is currently in trials to treat MDD (major depressive disorder), it was originally developed for the Defense Department as part of a program to enhance cognition (in that particular instance, in sleep deprived soldiers). In his answer Karl broadened the concept of cognitive enhancement, and introduced the idea of “anti-aging” of the brain.

This new class of potential drugs is widely referred to as nootropics. In a way, it is the perfect synthesis of regenerative medicine and human biology. As we age, it appears that we lose the ability to make as many “new” synaptic connections in the hippocampus, and in fact begin to lose the density of…

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · Ceretropic

I am very interested in the 90 day dosing, as my effects turned south past week 5. Perhaps the benefits become side effects the longer you are on it. Getting some hard data on that will be very interesting.

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NSI-189 sources---something everyone needs to understand about mentioning them.

Replying to sayitaintsoap · Are they any reports of someone hurting themselves due to NSI 189 use? I'm not aware of any.

I certainly got hyper-emotional on it. That was with normal dosages. Imagine what could happen if people start "megadosing" it, or mixing it with other things. I'm sure there are going to be some interesting results in t

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New Vendor Launch! www.ceretropic.com

Replying to zbrent · Congratulations! It is a pleasure to support a business that will advancing the state-of-the-art with compounds like GLYX-13. Have you considered manufacturing NSI-189 which stim

Definitely! It's been on our list for a while.

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Commentr/NootropicsNov 4, 2015

Tianeptine Sodium dose once a day.

Replying to srubek · Any reason why /u/misteryouaresodumb charges up the wazoo for it, then? Just curious.

It's expensive. All the Tianeptine labs just raised prices for everyone across the board by 25-30%. However, we did not raise prices. We actually lowered sulfate pricing. The increase is because demand is outpacing suppl

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Commentr/NootropicsSep 5, 2014

NSI-189 appropriate solvents for volumetric dosing? Anyone w/experience from longecity?

Replying to vdog26 · How come you don't sell them on your site?

We got a cease and desist from Neuralstem's lawyers, and decided it was not worth fighting.

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Commentr/NootropicsDepotAug 29, 2022

Fadogia vindicated?! https://pubmed.ncbi.nlm.nih.gov/35969364/

Replying to RarageInTheGarage · I wonder if NSI-189 would have passed under the old MARDS. It really sucks how that failed and didn't make it to market; there's nothing else out there quite like it. I do think NS

Well NSI-189 was assessed using both the MARDS and HAM-D-17 scales, and failed to reach clinical significance. However, it did reach clinical significance in the CPFQ (Cognitive and Physical Functioning Questionnaire) an

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