Comment · Tue, July 15, 2014 · Ceretropic
Seeing really good cognitive benefits from tianeptine
Original post in this thread
pittguy578 · 22 points
2nd week of tianeptine. I really like this substance. My mood is better., but the biggest benefit has been my love of learning and my ability to remember things is what it was before I started to suffer from extreme depression /stress.
Feeling like my old self from 5 years ago before I started suffering from literally debilitating depression. I am on WB and celexa for that and my mood has been stable off a while. The tianeptine seemed to give me a little boost.
But the main thing I noticed is the memory is coming back. I used to read articles/ papers all the time, but couldn't remember anything about them the next day. I had been able to do that before I started suffering from literally debilitating depression. Even after my mood was good it felt like I was still not back to where I was before. My love for learning has also come back. Even though my mood had improved I still would just like to vegetate and play video games. Now I would rather read and learn instead of blowing people up on BF4I know this is not a placebo. I had taken tons of other supplements/racetams in the hope I would get it back with not very good results. I wish I had discovered this substance a few years ba…
What they were answering
elegant_ejaculation · 1 points
Just be aware that tianeptine is considered an SSRE and supposedly works in direct opposition to Zoloft. If you don't notice much of an effect, it may be that the Zoloft is blunting the Tianeptine.
u/MisterYouAreSoDumb · Ceretropic
No, that is a misconception. It only has SSRE effects at higer doses, and it's never acting directly on the SERT. It's main actions are glutamatergic. That indirectly increases dopamine and norepinephrine in some areas of the brain, and lowers them in others. So classifying its actions as being from SRE activity is not correct.
It is actually used along side SSRIs, for treatment resistant depression.