Comment · Sat, February 22, 2014 · Ceretropic
Does Piracetam eventually stop working for everyone?
Original post in this thread
KanyesLawyer · 18 points
I've been reading a lot of posts and articles recently (on r/nootropics and other forums) that points to the sudden or gradual stop of piracetam's effectiveness. The effective period usually ranges from 6 months to up to 2 years.
I would like to consolidate more information regarding this, so feel free to share your own experiences. Do mention whether you take a choline source with piracetam, which ones specifically, and whether you started right away with a choline source or midway.
What they were answering
rugger2920 · 1 points
Do you have an opinion on whether this reverse tolerance method would also apply to Modanifil or other eugeroics, I understand they are not a stimulant per say but does possess some of the same characteristics. This would be quite a breakthrough if accomplished, at least for myself. These drugs work so well for me for a day or so but my tolerance builds remarkably fast similarly to my experiences with caffeine or any type of narcotic.
u/MisterYouAreSoDumb · Ceretropic
It's possible that is part of the mechanism. I think modafinil is a little more complicated, though. I think the enzyme induction plays a role in the perceived tolerance as well. Then there is the whole histaminergic system interactions that we don't fully understand yet.