Comment · Wed, January 15, 2014 · Ceretropic
Nicotine and cognitive decline
Original post in this thread
darbyhouston · 17 points
"Evidence suggests that non-smokers are up to twice as likely as smokers to develop Parkinson's disease or Alzheimer's disease.[106] A plausible explanation for these cases may be the effect of nicotine, a cholinergic stimulant, increasing the levels of acetylcholine in the smoker's brain; Parkinson's disease occurs when the effect of dopamine is less than that of acetylcholine. In addition, nicotine stimulates the mesolimbic dopamine pathway (as do other drugs of abuse), causing an effective increase in dopamine levels. Opponents counter by noting that consumption of pure nicotine may be as beneficial as smoking without the risks associated with smoking, although this is unlikely due to the importance of the MAO-B inhibitor compounds of tobacco in preventing neurodegenerative diseases."
Almeida OP, Hulse GK, Lawrence D, Flicker L (2002). "Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies". Addiction 97 (1): 15–28
---This is a summary of some cognitive effects of nicotine. I wanted to post this as an opening of a larger discussion on the cognitive effects of tobacco and nicotine in general.
---Do…
What they were answering
oncefoughtabear · 1 points
I was thinking about trying it out myself. How much do you chew?
u/MisterYouAreSoDumb · Ceretropic
I get the 4mg ones, since they are the same price as the 2mg. However, I cut them in half. 4mg is too much for someone that does not have a tolerance.