Comment · Wed, January 15, 2014 · Ceretropic

Nicotine and cognitive decline

Original post in this thread

darbyhouston · 17 points

"Evidence suggests that non-smokers are up to twice as likely as smokers to develop Parkinson's disease or Alzheimer's disease.[106] A plausible explanation for these cases may be the effect of nicotine, a cholinergic stimulant, increasing the levels of acetylcholine in the smoker's brain; Parkinson's disease occurs when the effect of dopamine is less than that of acetylcholine. In addition, nicotine stimulates the mesolimbic dopamine pathway (as do other drugs of abuse), causing an effective increase in dopamine levels. Opponents counter by noting that consumption of pure nicotine may be as beneficial as smoking without the risks associated with smoking, although this is unlikely due to the importance of the MAO-B inhibitor compounds of tobacco in preventing neurodegenerative diseases."

Almeida OP, Hulse GK, Lawrence D, Flicker L (2002). "Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies". Addiction 97 (1): 15–28

---This is a summary of some cognitive effects of nicotine. I wanted to post this as an opening of a larger discussion on the cognitive effects of tobacco and nicotine in general.

---Do…

What they were answering

oncefoughtabear · 1 points

Ive heard of people chewing nicorette aswell

u/MisterYouAreSoDumb · Ceretropic

I am chewing nicotine gum right now. It is very effective for memory, that is for sure.

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