Comment · Sat, March 9, 2013 · Ceretropic
Phenylpiracetam potential as an antidepressant?
Original post in this thread
_julain · 13 points
I've been using phenylpiracetam on and off for a few weeks, ~100mg sublingually, and I've noticed that aside from an increase in energy, it seems to lift my mood. I don't feel manic, elated, or any of that, I just feel good. I took ~100mg 3x today to combat my MDMA comedown and I've felt essentially normal all day. I've also used it to completely eradicate alcohol hangover symptoms (mainly the depressed, apathetic state they leave me in). Has anyone ever looked into phenylpiracetam as an antidepressant? Is there enough known about the compound to have any idea how it could improve my mood? I've heard other people report the same thing.
What they were answering
_julain · 2 points
Is it possible you get the irritability from a lack of choline? I remember reading one of your earlier posts about how other racetams have made you irritable as well. I wish personal MRI machines weren't unheard of.
Also, do you see any merit in taking DMAE as a choline source? I've been taking 200mg every time I take ~100mg of phenylpiracetam and I've never had that foggy headache some complain about when not getting enough choline while on racetams. But that could just be my brain chemistry. DMAE isn't known to cross the BBB, correct?
u/MisterYouAreSoDumb · Ceretropic
It's possible, but unlikely. I have tried all manner of combinations. If I am feeling irritable due to racetams, adding choline does not help. It can actually make it worse at times.
Also, do you see any merit in taking DMAE as a choline source?
It can convert to choline in the liver. However, then the choline cannot cross the blood brain barrier. It has not been proven that it can raise brain choline levels. Perhaps when taken with a methyl donor like trimethylglycine it might be able to. Although If you are having good results, I'd stick with it.