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Comment · Wed, January 30, 2013 · Ceretropic

Bupropion (Wellbutrin) as a nootropic?

Original post in this thread

coralto · 9 points

I was doing some research, and it turns out that Wellbutrin, which is commonly prescribed as an anti-depressant and as a quit-smoking aid, is actually considered substituted phenethylamine (notice anything else on that list?). It's not an SSRI or anything in that class, instead it works through norepinephrine-dopamine reuptake inhibition. Essentially it should increase the amount of dopamine in your system. Off-label it's been used for ADHD, sexual dysfunction, even weight loss. It's safe except for a slight increase of the chance of seizure.

Bupropion on wikipedia

What they were answering

mistermojorizin · 1 points

i haven't looked, i'm just sharing my own anecdotal experience along yours.

after reading this thread, and thinking about it, it did have a side effect at first. the first 2 weeks or so on the above dose (but not before then), i felt very spacey. but it went away after the first 2 weeks and i was surprised to find the improvement in memory.

edit: the wikipedia page has this line: "some improvement of cognitive and sexual functions" I didn't look into their sources, but they have them.

u/MisterYouAreSoDumb · Ceretropic

I'll have to do some more research into this. Most reports on Longecity say that it adversely affects any physical activity. Like it causes hypertension and heart palpitations.

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