Comment · Tue, January 29, 2013 · Ceretropic
GEBR-7B, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses.
Original post in this thread
MisterYouAreSoDumb · 32 points
It looks very interesting. It seems to selectively inhibit PDE4D in the brain, causing hippocampal cAMP (cyclic adenosine monophosphate) levels to rise. This enhances cascading signals via the adenylate cyclase pathway. The AC pathways are linked to various types of spatial and procedural learning.
Here is an article about type 3 AC receptors being involved in novel object recognition in mice.
Here is a full paper about AC type 5 being involved in plasticity and learning.
Here is an article about cAMP and Mg2+ involvement in long-term potentiation.
What they were answering
noopept_guy · 1 points
I'm vegan, so animals are out anyway. But I'm sure willing human subjects would be easy to find.
u/MisterYouAreSoDumb · Ceretropic
I leave for a little while and you guys are talking about either dosing homeless people with GEBR-7B or giving it to random animals. Haha