Comment · Mon, November 5, 2012
Redosing MDMA or use Amphetamine
Original post in this thread
[deleted] · 11 points
Hey /r/drugs,
I know that redosing MDMA increasing the neurotoxicity, so I am wondering if using Amphetamines instead of redosing would be less neurotoxic. Also later redoses mostly bring out speed-like effects, so I am assuming it would be better to just use actual speed.
The Amphetamine in question is pharmaceutical D-amphetamine (Dexedrine). I am going to a big EDM show in around 2 months and probably an after party, so I want to be able to keep on partying.
Thanks :)
What they were answering
zeekip · 2 points
I am not an expert, but one of the main reasons of MDMA's neurotoxicity is when serotonine levels are lowered, serotonine depleted cells take up the excesive dopamine resulting in nerve/cell damage. Taking amphetamines greatly increases this effect.
The second reason is oxidative stress, which can be reduced by taking anti-oxidants.
There are people here far better in telling you that, but I think I am pretty close.
u/MisterYouAreSoDumb
That is merely a hypothesis, not scientifically proven yet. But yes, you have the basic idea.