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774 matches · Lion’s mane
Is ErinaMax really the only standardized erinacine A Lion's Mane?
We launched Erinamax over 3 years ago. Oriveda just did theirs a couple months ago. Also, it's still the same raw material as ours. It's ErinaPrime, made by our partners in Taiwan Grape King Bio, who we co-developed the ingredient with. Look up the trademark on the USPTO. We came…
Eurycomax - my (almost 1 year update)
Replying to AAAUUUUAUAUAUUAUA · Very interesting to get those updates on the research front. Does the head clinician you mentioned only give erinamax for specific brain cancers or for all brain cancers? Im very c…
It's specifically in regards to coadministering it with radiation and/or chemotherapy to improve prognosis. It's not specifically for direct cancer-fighting effects. It's more a supportive effect to help your healthy brain cells survive while getting stronger treatment for the ca…
Eurycomax - my (almost 1 year update)
Replying to tyham · Super cool! Have any other trials been done with anything in your catalog? Will you try to release the results or is it mostly for internal use? Will you pre-register the trial?
Two on Erinamax. [Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study](https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2020.00155/full) [Effects of erinacine A-enrich…
UK supplement manufacturer actually runs his capsule and tablet machines with and without fillers and added ingredients, thought this is cool and informative
Replying to UniqueBasil1937 · Government also puts chlorine and fluoride in water so you don't get sick but it doesn't mean is good for you. They add anti-caking agents in table salts (calcium silicates and sil…
First off, MCC is the ideal filler for a bunch of reasons: * **Compressibility and flow:** MCC exhibits excellent powder flow properties. We us multiple grades (PH 101, PH 102, PH 200) for different formulation requirements. This enables consistent capsule fill weights and dosing…
⚠️ InfiniFiber is Now Live! Our Advanced Synbiotic Fiber⚠️
Replying to MrRADicalKMS · Crazy how it was, well still is, mostly Mycelium on grains, and now the market is finally moving towards real, potent Lion's Mane extracts that can actually provide legitimate effe…
Trust me, you have no idea! Myself and two of my people are on the AOAC functional fungi advisory board. We had to fight tooth and nail to keep the method call science-focused based around the bioactives in there. All the other players were just running interference on the scienc…
⚠️ InfiniFiber is Now Live! Our Advanced Synbiotic Fiber⚠️
Replying to CrimsonMax · Oh wow that's all amazing! Will you release Akkermansia as a standalone product or will it be in the probiotics? Oh wow, the optimized LM, will it contain all the 3 LM's currently…
Yes, standalone akkermansia. We would have already, but it is very unstable. Our production shipment was held in customs for a whole month, and it killed all the cells. We are trying to improve the shipping flow to make sure it doesn't happen again, which is why it is taking a wh…
⚠️ InfiniFiber is Now Live! Our Advanced Synbiotic Fiber⚠️
Replying to CrimsonMax · That is a very scary experience. I'm glad you got your wife to the ER as soon as you did! Dp you think Infinifiber can help with blood sugar and metabolic health in the long run? I…
Absolutely! The SFCA production from the probiotics in InfiniFiber will for sure help with blood sugar, insulin response, and metabolic health. This will be especially true when we release our Akkermansia, and then with our two comprehensive probiotics coming out. Akkermansia is…
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to Affectionate-Gas7526 · This is awesome. It's exactly what is needed in the industry, so people know exactly what they're getting. I own a small Lion's Mane Supplement brand. At heart, I'm a mushroom g…
Yes you can. Our hericene/hericenone method is the most comprehensive out there right now, testing a grouping of 10 of them. www.omnientlabs.com
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to AAAUUUUAUAUAUUAUA · Whoopsie. Yeah thats what i ment, your 1:1. Im very surprised that the Amyloban is that "one sided". It really does not look like it, no clue if i can blame the wobbly baseline or …
>Thats very interesting. I just did a quick google search and it does not seem to be very soluble in ethanol, it was about 0.5-1 mg/ ml in what im presuming to be 95% EtOH AND it seems to be very prone to oxidation. The patent, if i remember correctly, states that the raw materia…
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to AAAUUUUAUAUAUUAUA · Whoopsie. Yeah thats what i ment, your 1:1. Im very surprised that the Amyloban is that "one sided". It really does not look like it, no clue if i can blame the wobbly baseline or …
> Im very surprised that the Amyloban is that "one sided". It really does not look like it, no clue if i can blame the wobbly baseline or if i just have to bite the bullet and get glasses. You have to look at the actual peak areas numbers below the chromatogram, and then look at…
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to AAAUUUUAUAUAUUAUA · I could be because of the scale but based on just eyeing the chromatograms it seems like your extract is quite similar in the proportion of hericenes, but ill take your word for it…
> I could be because of the scale but based on just eyeing the chromatograms it seems like your extract is quite similar in the proportion of hericenes, but ill take your word for it since you are the man with the numbers. Well that's not our extract. It's our 1:1 powder. However…
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to AAAUUUUAUAUAUUAUA · Thanks, thats pretty interesting. The only real differences that i can see are that the proportion of hericenone F-H to hericenone C-E is different, it seems like yours has way mor…
Yes, ours is more heavy on hericene A/B and C, along with hericenone C and D, and has more total peaks. Amyloban has more hericenone F and G and fewer peaks. We also have two more unlabeled peaks that we think are hericenes/hericenones, but are still structurally elucidating. Our…
Curious on y'alls thoughts on this. I spoke to a ayurveda person (ayurveda is where Ashwagandha and Bacopa come from) and he was like for thousands of years we put the herbs into food and ate it long-term and not made extracts out of it. Should we have skepticism over extracts with this logic maybe?
Replying to DoctorBoneMarrow · Thank you! >Vitamin D is deficient in a lot of people, and it affects dopaminergic signaling, so that would be an easy one to add in And deficiency is linked with more severe sym…
That risperidone study is actually pretty compelling for showing astrocyte metabolism matters in the basal ganglia. If I were targeting hypoactive astrocytes specifically, here's what I'd try: * Lion's Mane- The hericenones and erinacines directly stimulate NGF synthesis from ast…
Erinamax research
This is another paper: [Efficacy of Combined Hericium erinaceus Mycelium and Undenatured Type II Collagen in Reducing Osteoarthritis Progression in a Preclinical Animal Model](https://www.medsci.org/v23p0815.pdf)
The story behind the FDA raid of Nootropics Depot
Replying to AAAUUUUAUAUAUUAUA · That would be super cool to get some more data on lions mane bioactives, however, one thing that i had not really thought that much about until recently is that probably a signific…
Well yeah, that happens all the time with the glycosides in plants. Our body usually cleaves off the glycoside groups before they go to work in the body. It's like the difference between baicalin and baicalein. The glycosides make the compound more water soluble, then the body ri…
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to AAAUUUUAUAUAUUAUA · Any updates on hericenone and hericene content in the 8:1 or the amyloban testing? Or anything else exciting.
Actually, yes! [Here is the chromatogram from the Amyloban lion's mane](https://imgur.com/a/Pj7257e). We found 1.38mg of hericenes and hericenones per capsule. That's getting really close to our 1.7mg per capsules for our 1:1, but not quite there yet.
Behind the Scenes at Nootropics Depot: Inside Our Pharmaceutical-Grade Testing Labs 🧪
Replying to ProperBeat · I saw some omnient test reports on oriveda's website already
Yep, they recently sent us samples for testing. They were finally able to get an erinacine A product that contained it. It's much different than the one they have been selling for years. That old one had no erinacines in it. This new one does. Funny enough, we bought some of the…
Our Black Friday Sale 2025 is officially live!
Replying to OpossumSambhava · Wait, so I'm a little confused-- Erinamax is identical to the Taiwanese extract, which caused dysphoria? Surprising, as that was not my experience with it.
No, the extract I was using was made from the Taiwanese material where we were unknowingly destroying the erinacine A in the extraction process. It actually led us to understand the stability of the molecule better. Grape King Bio in Taiwan had their interest spurred when they sa…
Our Black Friday Sale 2025 is officially live!
Replying to [deleted] · [deleted]
> Are you thinking of releasing the mushroom as a standalone as well, or just in a stack? It will be in the stack at first, then standalone afterwards. >Is it a "common" mushroom? Is there a decent amount of literature on it? It is a "common" mushroom in that it is related to one…
Our Black Friday Sale 2025 is officially live!
Replying to AAAUUUUAUAUAUUAUA · Very exciting, just dont release too much cool stuff, i need to stay around 300 dollars in total and ill probably need to stock up on some essentials by then... Ive seen some of t…
No, new designs will not raise prices. Bottle cost will go up, but our label cost might actually go down. Printing in house costs a lot, with the cost of stock, ink/toner, and maintenance of our printers. Having a professional printing company do them for us can actually make it…
What makes Erinamax Vegetarian but not Vegan?
Replying to CrimsonMax · You know when you told me about the 1:1 LM having 2-3x more hericenones now, I do want to stack it with Advanced Blend. LM aside, my all time mushroom has always been Cordyceps, es…
We are doing custom extracts of lion's mane and reishi right now, trying to optimized some novel extraction processes. After that, we can work on Cordyceps extractions. We are also trying to determine the unique bioactives in both Tiger Milk and White Jelly, then create standardi…
Myostatin Mushroom
Replying to Warren_sl · It is very interesting! It seems to have had some effectiveness for me if not anecdotal and in context of being used alongside my stack but In ‘23 and ‘24 I got a Novavax with a ce…
I caught Omicron. I was very sick, and it took me a month to test negative. I've had friends get Delta and have it be very mild. Then I have had other friends totally rocked by it. Same for each strain, really. Some people just react more strongly than other to specific ones. I h…
What makes Erinamax Vegetarian but not Vegan?
Replying to CrimsonMax · I had no idea about these studies, I'll have to read them both! Will you guys do studies on what happens if BOTH erinacine A and hericenones are consumed? I feel like that would ha…
Yeah, most people around the world have based their erinacine A research off Wojciech's 15 year old paper he did. [Erinacine A biosynthesis in submerged cultivation of Hericium erinaceum: Quantification and improved cultivation](https://analyticalsciencejournals.onlinelibrary.wil…
What makes Erinamax Vegetarian but not Vegan?
Replying to CrimsonMax · Yoooooo! I had no idea there was a study that used ErinaMAX!!! That's exciting stuff lol
Yep! This study as well. [Effects of erinacine A-enriched Hericium erinaceus on elderly hearing-impaired patients: A double-blind, randomized, placebo-controlled clinical trial](https://www.sciencedirect.com/science/article/pii/S1756464622002900) These are our partners in Taiwan…
What makes Erinamax Vegetarian but not Vegan?
Replying to CrimsonMax · That's super cool! I have a feeling ErinaMAX could be a breakthrough for Alzheimer's disease and maybe for other kinds of mental ailments, who knows! I ordered Advanced Mushroom Bl…
Well you have seen the study on Erinamax and early onset Alzheimer's, right? [Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study](https://www.frontiersin.org/journals/aging-neuroscience/articles/1…