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Comment · Fri, July 21, 2023 · ND Owner

Could someone help me understand how ND Berberine compares to Thorne's Berberine?

Original post in this thread

SnackyFace · 8 points

Here are the two products:

- https://nootropicsdepot.com/berberine-phytosome-capsules-550mg/

- https://www.thorne.com/products/dp/berberine-500

Obviously more numbers doesn't mean more better. However, Thorne has a 550mg Berberine Phytosome like ND does, and 450mg more of Berberine HCl while ND does not.

Can someone explain if this is a significant difference in products and what Thorne is trying to accomplish compared to ND? Thorne doesn't say it has 28% Berberine in the complex so I guess theoretically the number is lower compared to ND? How does the 450mg of the Berberine HCl alter the equation? Is this a matter of one product is superior to the other, or are they both designed for different purposes?

I figured I'd ask here because someone has probably done the comparison before. I tend to go to ND first for a product and go to Thorne/somewhere else if ND doesn't offer. This caught my attention and I figured someone else might benefit from this information, too.

Thanks!

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · ND Owner

Some people get digestive upset with regular berberine HCL, but don't with the phytosome. We sell berberine HCL tablets with silymarin as a different product.

https://nootropicsdepot.com/berberine-hcl-silymarin-tablets/

That's because research has shown that berberine combined with silymarin works better than it on its own.

https://onlinelibrary.wiley.com/doi/full/10.1002/ptr.6282

I don't see a reason to combine the phytosome with the normal HCL, but we might be up for an optimized berberine stack at some point in the future. I personally just use the phytosome now.

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