Comment · Fri, September 2, 2022 · ND Owner
Milk Thistle (Silymarin)
Original post in this thread
AnabolicGreyhound · 15 points
Planning on adding this to my workout + cognitive stack including TA, Cistanche, Shilajit, Ecdysterone, Schisandra, Rhodiola, Apigenin.
I’m not as well studied on Silymarin, can anyone advise whether it exerts any anti-androgenic activity or may inhibit ‘gainz’ through strong antioxidant activity?
If the answer to this is no, I may well combine with TA, Shilajit, Cistanche and my first meal of the day.
What they were answering
Ratharax · 8 points
I made a post on this on this sub. Search the sub.
Silymarin is an extremely potent disruptor of a transmembrane protein that transports thyroid hormone. Particularly one component of silymarin, called silichristin, does this very strongly.
Edit: ill save you a sec, here's the link:
Edit: also i clearly didnt take in your post before writing my comment. Thyroid hormones arent androgens. Still something to consider though.
u/MisterYouAreSoDumb · ND Owner
So we have been able to make a silichristin-free (or very low) milk thistle. Issue is that it is going to be more expensive. Is this something you would be interested in, and do you think this would be a good thing for the bodybuilding community? I know a lot of people in that community use milk thistle, and they are likely unaware of the thyroid effects. If they had an alternative without silichristin do you think they would value that enough to pay a bit more?