Comment · Fri, June 10, 2022 · ND Owner
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Original post in this thread
NDSocialMedia · 55 points
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What they were answering
parisg · 1 points
u/MisterYouAreSoDumb
What about the possible kidney damage associated with ecdysteroids?
u/MisterYouAreSoDumb · ND Owner
Interesting study and mechanism. However, those studies are on ecdysone, not beta ecdysterone (20-hydroxyecdysone). They are different molecules.
https://www.mdpi.com/2227-9059/9/5/492/htm
That's a phase 2 trial for beta-ecdysterone (20-hydroxyecdysone). They don't move to phase 2 without safety data.
The aim of this review is to describe the potential and challenges in developing 20-hydroxyecdysone (20E) as a pharmaceutical agent for the future. It is a natural plant steroid with low mammalian toxicity and accumulated data from academic and pre-clinical studies
So while the studies on the similar compound ecdysone are interesting, I am not sure it applies to beta ecdysterone.