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Comment · Sun, May 8, 2022 · ND Owner

Any benefits of stacking nobelitin with apigenin?

Original post in this thread

JosephinesOtherMan · 11 points

Wondering if there would be any synergy between all of these bioflavanoids or if it makes sense to just take one at a time.

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Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · ND Owner

Yes, they should go well together. Nobiletin is a very interesting flavonoid that doesn't get enough attention.

The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro

It modulates cAMP/CREB as well, so it should help with memory and cognition. It modulates NF-κB, so it should help with inflammation. I would certainly try each on their own first, to see how you respond. However, doing a combo with them should provide some synergy in effects.

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