Comment · Sun, May 8, 2022 · ND Owner
Any benefits of stacking nobelitin with apigenin?
Original post in this thread
JosephinesOtherMan · 11 points
Wondering if there would be any synergy between all of these bioflavanoids or if it makes sense to just take one at a time.
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
Yes, they should go well together. Nobiletin is a very interesting flavonoid that doesn't get enough attention.
The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro
It modulates cAMP/CREB as well, so it should help with memory and cognition. It modulates NF-κB, so it should help with inflammation. I would certainly try each on their own first, to see how you respond. However, doing a combo with them should provide some synergy in effects.