Comment · Sat, March 19, 2022 · ND Owner
Why would 7,8 DHF make me want to end my life?
What they were answering
[deleted] · 1 points
[deleted]
u/MisterYouAreSoDumb · ND Owner
Lots of the flavonoids, like baicalein in our baikal skullcap, hit GABA-A.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4863311/
Ginger is also anxiolytic.
https://pdfs.semanticscholar.org/5478/139d9dbe7d06f37efbad9c90d1b99d65f1b7.pdf
Apigenin might be good, too.
https://sci-hub.se/10.1016/j.ejphar.2004.08.043
GABA-B is a bit more difficult. Emoxypine just sensitizes GABA receptors. It doesn't bind to them like traditional anxiolytics. It's good to combine with other things that hit GABA, though. That's where it shines.