Comment · Wed, February 24, 2021 · Natrium Health & Nootropics Depot
Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men: "results indicate that GAA as a preferred alternative to creatine for improved bioenergetics in energy-demanding tissues"
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gintrux · 74 points
Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men
In this randomized, double-blind, crossover trial, we evaluated whether 4-week supplementation with guanidinoacetic acid (GAA) is superior to creatine in facilitating creatine levels in healthy men (n = 5). GAA (3.0 g/day) resulted in a more powerful rise (up to 16.2%) in tissue creatine levels in vastus medialis muscle, middle-cerebellar peduncle, and paracentral grey matter, as compared with creatine (P < 0.05). These results indicate that GAA as a preferred alternative to creatine for improved bioenergetics in energy-demanding tissues.
https://sci-hub.do/10.1139%2Fapnm-2016-0178
More studies: https://www.reddit.com/r/Nootropics/comments/gx7pgw/guanidinoacetic\_acid\_precursor\_to\_creatine/
What they were answering
fortis_adipo · 1 points
Great, I'll be on the lookout for it. Late ask, but do you think you'd stock any Ampakines soon? I think they're one of the most effective but overlooked/undersold noots out there: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114293/
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
Racetams are technically AMPAkines. Are you referring to other specific ones?