Comment · Sat, December 19, 2020 · ND Owner
What is the role of pyroglutamic acid in the alcohol defense formula?
Original post in this thread
Bierak · 5 points
One of the problems that I have developed over time when I drink alcohol is that it increases the frequency and ease of developing "blackouts", added to that the rebound effect of anxiety has also increased over time. When I was younger, I didn't get those blackout effects.
I wonder if pyroglumatic acid is included in the formula to prevent the harmful effects of alcohol on the NMDA receptor. As I know alcohol works by activating GABA receptors and by blocking NMDA receptors, it is the combination of both that produces the rebound anxiety and the blackouts. The main problem with alcohol for me right now are the blackouts. I also drink less amount and less frequently than when I was young but as you can know it is difficult to not drink when you socialize
What they were answering
Bierak · 1 points
Last time I took like 3 cans of 450 ml of beer, 3 small botles 350 cc of beer, one glass of whiskey, some wine. Before that, two weeks ealier I drank a similar amount of beer 5 - 6 cans of 450 ml, then one glass of a distilled beverage (pisco). On two occasions I blacked out.
I also think this does not say something good about the health of my brain. I dont drink very often, I'm not a every weekend drinker anymore.
And on both times I took Nac, Vit c before drink, and then pills with grape seed, alcar, na-r-ala as a basic antioxidant stack.
So perhaps I drink more than my NMDAr can handle, perhaps by counteracting the intoxicating effects of alcohol by antioxidants. I dont loose posture, motor and speech function before the black outs. For example a friend of mine always tell me that he stop to drink when he starts to feels slurred speech and loss of fine motor skills.
I did an CT Scan on October and nothing abnormal were found. However I have some symptoms of mild brain fog and inflammation that I manage with supplements. Basically It feels like I dont have good blood irrigation to the left side of my brain, dont know If It is a connective tissue problem, muscular rigidity, or vascular sclerosis, I have talked with doctors about It. It is the feeling of a compression or rigidity on the back of the neck/head but as always "nothing wrong here, I doubt It is a vascular problem…
u/MisterYouAreSoDumb · ND Owner
Yeah, that's a lot for someone in their 30s who doesn't regularly drink. Most people have to drink less as they get older, unless they drink all the time to keep their tolerance up. I rarely drink more than 3 beers these days.