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Comment · Fri, October 30, 2020 · ND Owner

Supplements with a reverse tolerance?

Original post in this thread

Beachday4 · 8 points

What supplements have a reverse tolerance. I’ve heard that Fasoracetam actually gets stronger overtime, same with Polygala. Wondering what other supplements have a similar effect.

What they were answering

srubek · 9 points

Echinacea angustifolia Root Extract EP107 -- effect builds with weeks of dosing. The only product on the market containing it, is Anxiocalm by "Terry naturally" (same people who introduced curcumin's really bioavailable extracts within the US), and I want /u/misteryouaresodumb to stock their own EP107 standardized extract!

Clinical research shows fast-acting results. In one study, the special extract of Echinacea angustifolia (EP107™) was tested with individuals experiencing increased anxiety and tension. After just one day, the participants noticed a reduction in stress and anxiety, with an even greater reduction in just seven days.
In a further study, seven types of echinacea extracts were compared to the prescription anti-anxiety drug, chlordiazepoxide (also known by the brand name Librium® ). Only one echinacea preparation demonstrated a robust ability to reduce anxiety in a wide dosage range comparable to the prescription drug—the unique Echinacea angustifolia extract.
This special echinacea root extract not only met the drug’s anti-anxiety effects, it exceeded them. It also didn’t cause any drowsiness—a common side effect of prescription drugs for anxiety. Aside from drowsiness and lethargy, the other adverse effects for chlordiazepoxide include confusion, edema, nausea, constipation, menstrual abnormalities, jaundice, altered libido, involunta…

u/MisterYouAreSoDumb · ND Owner

I can look into it, but magnolia bark does the same thing, and works really well for stress already. It sounds like they made something similar to our magnolia bark, but from Echinacea angustifolia root.

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