Comment · Mon, September 28, 2020 · ND Owner
KSM-66 and downregulation of serotonin receptors
Original post in this thread
sekxbuttox · 8 points
Does anyone have any studies showing this is true? I've heard people say that with prolonged use it can cause side-effects similar to those of SSRIs. Is it something that we should be wary of? I don't want to do any permanent damage.
I'm also curious about your opinions on whether KSM should be cycled or not. I'm thinking of doing 1 month on/1 week off. This good?
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
So it appears that it sensitizes 5-HT2A receptors and desensitizes 5-HT1A.