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Comment · Sat, September 5, 2020 · ND Owner

Glycine?

Original post in this thread

ActualThrowaway7856 · 5 points

Is there any chance of Nootropics Depot selling Glycine? I definitely do not trust any other company with something as cheap and simple as glycine since it's so easy to fake it. I'm interested in taking it with creatine to alleviate symptoms of sluggish cognitive tempo.

What they were answering

johnnycoconut · 2 points

So just to get this clear, magnesium glycinate exerts its effects in the body as magnesium ions (\~14% by mass) and glycine (\~86%)?

u/MisterYouAreSoDumb · ND Owner

Magnesium glycinate is elemental magnesium chelated to two glycine molecules by a coordinate bond. That's a bond that is not as strong as a covalent bond, but not as weak as a peptide or ionic bonds. Your body can dissociate coordinate bonds. So a dose of magnesium glycinate will dissociate to elemental magnesium and glycine in serum. It just won't break down in the GI tract like a peptide or ionic bond would.

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