Comment · Fri, September 4, 2020 · ND Owner
Glycine?
Original post in this thread
ActualThrowaway7856 · 5 points
Is there any chance of Nootropics Depot selling Glycine? I definitely do not trust any other company with something as cheap and simple as glycine since it's so easy to fake it. I'm interested in taking it with creatine to alleviate symptoms of sluggish cognitive tempo.
What they were answering
Bajawah · 2 points
Do you have a place you would purchase from if you were in our shoes?
u/MisterYouAreSoDumb · ND Owner
Not at the moment, unfortunately. Maybe if I saw a COA for that specific lot, and everything looked okay to me. The issue is that testing amino acids can be difficult. You need special sample prep and methods. They differ from other small molecule organics. Take glycine for example. There is no chromophore. So an HPLC/UPLC can't "see" it. You have to do precolumn derivatization for each amino acid. This attaches other groupings to them to allow your machines to see the aminos and separate them from each other. They are also notorious for not separating in an HPLC column. This is also why peptides are hard to test. Peptides are long chains of amino acids. So they are extra difficult.