Comment · Mon, August 10, 2020 · ND Owner

Cycling NMN

Original post in this thread

ROTHUM2 · 13 points

First off, I’ll say that ND’s NMN is by far the best I’ve tried. But, like most NMN products I notice a decline in efficacy after maybe 1 week.

I’m considering cycling 1 week on, 3 days off, or something similar.

I’m curious if you’ve all noticed something similar.

My dosage is 250mg in the morning, but I can take another dose late afternoon without noticing it too much. I find it works in the background and isn’t too stimulating.

What they were answering

Fusion_Health · 1 points

Interesting. I see the AMPK and MAOI effects, how does the tongkat fit in? CoQ helps in terms of ATP synthesis?

Might have to check out berberine next, haven’t played around with that one.

u/MisterYouAreSoDumb · ND Owner

CoQ10 is helping with ATP synthesis in the electron transport chain. Tongkat is likely testosterone related, but I think c-Fos is playing a role as well.

https://www.researchgate.net/profile/Jamil_Kazi/publication/304196199_AENSI_Journals_Advances_in_Environmental_Biology_Corresponding_Author_Eurycoma_longifolia_Jack_Tongkat_Ali_induced_c-Fos_Expression_in_Sensory_and_Motor_Neurons_of_the_Rat_Brain_Nervous_System/links/5769415a08ae1a43d23a2e48/AENSI-Journals-Advances-in-Environmental-Biology-Corresponding-Author-Eurycoma-longifolia-Jack-Tongkat-Ali-induced-c-Fos-Expression-in-Sensory-and-Motor-Neurons-of-the-Rat-Brain-Nervous-System.pdf

Tongkat also activates cAMP. So it appears that tongkat ali is modulating multiple brain systems, in addition to its increase of testosterone.

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsDepotOct 16, 2020Nootropics DepotND Owner

u/MisterYouAreSoDumb which product(s) are you most proud of?

Hmm, I am proud of a lot of them. I would say tongkat ali or NMN for effects and how much I personally like them. I would say Shoden for the scientific work we put in to it. I am honestly still very proud of Immune Defen

41Tongkat aliAshwagandhaNMN

Commentr/NootropicsDepotAug 3, 2020Nootropics DepotND Owner

What does /u MisterYouAreSoDumb take?

I am always trying new things that we are working on. So at any one point in time my stack will be different. However, I do have some staples in my base stack that stay there pretty consistently. * CoQSol-CF * Reacta-C

40Tongkat aliAgmatineDosingNMN

Commentr/NootropicsDepotJan 9, 2021Nootropics DepotND Owner

MisterYouAreSoDumb, what is your current stack and why?

My base stack stays pretty consistent, but I have modified some things. * Reacta-C * Vitamin D3/K2 (not released yet) * CoQSol-CF * Our Yeast Extract * Microzinc * Berberine/Silymarin * Our EGCG tablets * Our (-)-epicat

34BacopaTongkat aliAgmatineQuercetin

Commentr/NootropicsDepotFeb 28, 2021Nootropics DepotND Owner

Best for work, focus, and energy

I would say CoQSol-CF, NMN, DynaMAX, PanaMAX, and tongkat ali. For someone that struggles with low energy, but also anxiousness, that's a good stack to hit on a balanced effect. The CoQSol-CF and NMN give a nice natural

15Tongkat aliL-theanineNMN

Commentr/NootropicsDepotOct 28, 2020Nootropics DepotND Owner

Tongkat Ali Nausea

It's really hard for me to help on this one, because I just don't get the same nausea. I take a 2% and 10% tongkat, along with berberine, silymarin, NMN, EGCG, CoQSol-CF, Microzinc, and yeast extract all at the same time

14Tongkat aliNMNMilk thistle

Commentr/NootropicsDepotApr 15, 2022Nootropics DepotND Owner

New releases, who this?

Replying to hagosantaclaus · Tagging on to this, and with all due respect, I have to ask the ever recurring and hopefully not yet annoying question, what is your current stack u/misteryouaresodumb?

* Reacta-C (Literally the only thing I take from another brand now) * Our yeast extract * CoQSol-CF * D3/K2 * EGCG * Microzinc * Andrographis * Tongkat 10% * Cistanche * Epicatechin * NMN enteric * Reduced glutathione *

13Tongkat aliCistancheAshwagandhaQuercetin